A new human tumor-associated antigen (TLP) is naturally expressed in rat DHD-K12 colorectal tumor cells
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Immunity, Is Widely Expressed in Gynecological Tumors cdr2, a Target Antigen of Naturally Occurring Human Tumor
The paraneoplastic neurological disorders provide perhaps the best known example of naturally occurring tumor immunity in humans. For example, patients with paraneoplastic cerebellar degeneration (PCD) appear to suppress the growth of occult breast or ovarian tumors that express a neuronal antigen termed cdr2. PCD patients harbor cdr2specific CTLs in their peripheral blood, and these cells are ...
متن کاملCdr2, a target antigen of naturally occuring human tumor immunity, is widely expressed in gynecological tumors.
The paraneoplastic neurological disorders provide perhaps the best known example of naturally occurring tumor immunity in humans. For example, patients with paraneoplastic cerebellar degeneration (PCD) appear to suppress the growth of occult breast or ovarian tumors that express a neuronal antigen termed cdr2. PCD patients harbor cdr2-specific CTLs in their peripheral blood, and these cells are...
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A monoclonal antibody (K-1-21) raised against a kappa Bence Jones protein exhibits unique binding properties to malignant plasma cells. K-1-21 is an IgG1 kappa antibody that reacts with human kappa light chains in free form, but shows no reactivity with heavy chain-associated kappa light chains. By immunofluorescence, K-1-21 binds to the surface of LICR LON/HMy2 (HMy2) kappa myeloma cells and t...
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PURPOSE A prerequisite for the development of vaccination strategies is the identification and characterization of relevant tumor-associated antigen. Using microarray and reverse transcription-PCR analysis, we found matrix metalloproteinase (MMP)-7 to be extensively up-regulated in renal cell carcinomas and expressed in a broad variety of malignant cells. MMP-7 can promote cancer invasion and a...
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DKK1 IS A WIDELY EXPRESSED AND POTENT TUMORASSOCIATED ANTIGEN IN MULTIPLE MYELOMA Jianfei Qian, Jin Xie, Sungyoul Hong, Jing Yang, Liang Zhang, Xiaohong Han, Michael Wang, Fenghuang Zhan, John D. Shaughnessy, Jr., Joshua Epstein, Larry W. Kwak, and Qing Yi Department of Lymphoma and Myeloma, Division of Cancer Medicine, and the Center for Cancer Immunology Research, The University of Texas M. D...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2000
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(20000215)85:4<540::aid-ijc16>3.0.co;2-v